Higher-education leaders, accreditors and campus administrators are confronting how generative AI is reshaping teaching, research, and administrative work and are calling for system-level changes to faculty roles, HR, and accreditation standards. Analysis argues AI will automate routine tasks across instruction, research synthesis, advising and back-office enrollment work, and that institutions must redefine faculty and staff responsibilities to protect core human functions like mentoring and scholarship. Separately, a founder who built an AI therapy app shut the product after concluding chatbots pose safety risks for vulnerable users, underscoring real-world limits to deploying AI in student mental-health services. Institutions are being urged to adopt risk-aware governance: accreditors can set expectations for oversight, and campus mental-health providers should treat AI as a tool requiring human supervision.