The Chan Zuckerberg Initiative cut roughly 70 positions—about 8% of its staff—as the Zuckerberg family refocused its philanthropy on AI‑driven biomedical research and the Biohub network. CZI confirmed layoffs at its Redwood City headquarters and said severance and support were provided for affected employees. Mark Zuckerberg and Priscilla Chan have signaled a strategic pivot away from earlier education and social‑justice ventures toward science-heavy projects; Zuckerberg said Biohub will be the philanthropy’s main focus. The shift mirrors a broader trend of big donors concentrating resources on biomedical and tech-enabled science initiatives. Why it matters: Large philanthropic reorientations change the research and partnership landscape for universities—redirecting grant flows, collaboration opportunities and philanthropic staffing models that many academic labs and centers rely on.