Newly released Justice Department records linking academics and university programs to Jeffrey Epstein have forced personnel changes and program disruptions across multiple campuses. Institutions reported department chairs and trustees stepping down, conferences canceled, and interdisciplinary centers closed after names surfaced in the files. Universities cited public pressure and internal reviews as the immediate catalysts: the School of Visual Arts and Union College lost senior figures; Duke announced closure of three interdisciplinary centers after mentions in the files; and students at several campuses staged protests demanding transparency and accountability. Scholars and campus ethicists called the moment “a reckoning” for institutional donor oversight and governance. Campus leaders should expect continued reputational risk, trustee inquiries, and donor‑vetting demands. Board chairs, general counsels, and development offices will need to coordinate rapid reviews of donor histories, conflict‑of‑interest policies, and transparency protocols while sustaining academic integrity and research continuity.