A landmark 25-year-old study on glyphosate, the active ingredient in Roundup, has been retracted, prompting scientists, regulators and public-interest groups to call for the Environmental Protection Agency to reassess the chemical’s safety. The retraction revives scrutiny of long-standing literature that has informed regulatory and academic positions on herbicide risk. Research administrators and university labs that collaborate on environmental toxicology research should expect renewed requests for data access, reexamination of prior risk assessments, and potential shifts in grant priorities tied to pesticide and public-health research.