American student applications to universities abroad in Europe, the UK, and Asia are rising amid growing concerns about affordability and political uncertainty domestically. Meanwhile, international enrollment at U.S. regional publics and smaller private colleges is declining, with traditional large, selective institutions maintaining stronger shares. INTO University Partnerships and Universidad InterNaciones exemplify global networked higher education, offering international students customized programming and online education to increase access, mobility, and student success. Partnerships between institutions across countries are increasingly important in facilitating flexible, global learning paths amid shifting geopolitical and economic landscapes in higher education.