Jeffrey R. Holland, a longtime leader in the Church of Jesus Christ of Latter-day Saints and former president of Brigham Young University, died at 85 from complications of kidney disease. Holland’s death creates a vacancy in the Quorum of the Twelve Apostles and removes a senior figure who shaped BYU’s academic and interfaith initiatives. University administrators and regional higher-education partners will be watching succession at church leadership for implications on BYU governance, international programs, and religious-affiliated education policy.