Johns Hopkins laid off about 110 employees in response to federal research spending cuts, according to a university spokesperson. The reductions largely hit administrative roles, following prior budget-savings efforts intended to delay layoffs. The article ties the cuts to a sharp federal grants decline: Johns Hopkins’ federal research grants dropped by about $500 million last year, and the downward trend continued into 2026. President Ron Daniels’ earlier message cited the need to change the “infrastructure” supporting shrinking federal portfolios. Alongside workforce reductions, Johns Hopkins is planning budget shifts—cutting 10% from its administrative budget and pursuing more cost-efficient research operations through technology and reduced duplication—while also seeking new revenue through corporate research partnerships and new academic offerings.