The National Institutes of Health agreed in court filings to reexamine hundreds of grant applications that it had previously shelved or denied under the prior administration. The reversal follows litigation and administrative pushback over funding decisions made late in the year. The agency’s re‑review could free research dollars for university investigators and reverse a period in which controversial policy choices limited federal support for certain lines of inquiry. University research offices and principal investigators should prepare for requests to resubmit or provide supplemental information as NIH revisits those proposals.