J. Michael Bishop, a Nobel Prize laureate who helped identify cancer‑causing genes and later served as chancellor of the University of California, San Francisco, has died at 90. Bishop’s research was foundational to molecular oncology; as UCSF chancellor he oversaw significant expansion of the campus’s biomedical research footprint. Colleagues and university leaders note his dual legacy as a laboratory scientist and an institutional builder. His death will prompt universities with major biomedical programs to reassess mentorship pipelines and the stewardship of translational research centers that trace lineage to his work.