Johns Hopkins University laid off about 110 employees in administrative roles in response to federal research spending cuts, according to the school’s spokesperson. The layoffs follow budget-savings efforts and arrive after Johns Hopkins reported its federal research grants dropped by roughly $500 million last year, with declines continuing into 2026. The university said it is shrinking research operations’ cost structure through technology, reducing duplication, cutting 10% from the administrative budget, and seeking revenue diversification via corporate partnerships and new academic offerings. President Ron Daniels has tied the workforce changes to an increasingly austere, less predictable federal funding environment. The impact is notable for the broader research sector: private and public research universities are reshaping central research infrastructure, shifting personnel away from grant administration capacity while trying to preserve compliance and sponsor reporting as portfolios contract.