A landmark 25‑year paper on glyphosate, the active ingredient in Roundup, has been retracted, prompting scientists and public‑health advocates to urge the EPA to reassess the herbicide’s safety profile. The retraction has reignited policy and regulatory conversations around long‑standing chemicals and the evidence base used in federal approvals. Researchers and watchdogs point to methodological concerns and the need for fresh, transparent reviews of glyphosate’s health risks. The development will ripple across university toxicology and environmental‑health programs that collaborate with regulators and industry. Universities conducting pesticide and environmental‑health research may face renewed scrutiny of data standards and disclosure practices as federal agencies consider whether prior assessments should be revisited.