A new U.S. mental health and substance use report shows encouraging declines in several adolescent substance-use and mental-health indicators even as officials and researchers stress the need for continued treatment access. The National Survey on Drug Use and Health, released by the Substance Abuse and Mental Health Services Administration (SAMHSA), includes trends from 2021 to 2025 after uncertainty following a prior staffing change in the survey program. The report finds fewer adolescents (ages 12 to 17) reporting tobacco, alcohol, marijuana use, binge drinking, and fewer reported substance-use disorders and starting behaviors such as vaping or initiating alcohol. It also reports declines in major depressive episodes and serious thoughts of suicide. However, the survey also highlights persistent challenges: nearly 20% of adolescents report moderate or severe anxiety symptoms, and policy advocates note that access to quality substance-use treatment still remains far below need. For higher education institutions and student-support offices, the signals reinforce that student well-being improvements may be uneven—creating continued demand for campus counseling capacity, early intervention, and referral systems that can translate survey-level trends into effective supports on campus.